Rheumatology

Condition or Disorder Intervention vs. Control Outcome Follow-up Duration Event Rates % NNT (95% CI)
CER EER
Calcific shoulder tendinitis1 Pulsed ultrasound vs. sham therapy Changes from baseline in shoulder calcium deposits on radiography, pain, active range of motion and power of shoulder and activities of daily living were assessed. 9 months 8 42 3 (2 to 9)
Carpal tunnel syndrome2 Injection of methylprednisolone and lignocaine vs. lignocaine alone (control) Symptom improvement-defined as having no symptoms or minor symptoms requiring no further treatment 1 year 7 50 3 (2 to 9)
Rheumatoid arthritis3 Intravenous infusion of infliximab, 3mg/kg of body weight every 4 weeks vs. placebo Response rate (defined as 20% improvement from baseline according to the 1987 American College of Rheumatology criteria) 30 weeks 20 53 4 (3 to 6)
Intravenous infusion of infliximab, 3mg/kg every 8 weeks vs. placebo 20 50 4 (3 to 6)
Intravenous infusion of infliximab, 10mg/kg every 4 weeks vs. placebo 20 58 3 (2 to 5)
Intravenous infusion of infliximab, 10mg/kg every 8 weeks vs. placebo 20 52 4 (3 to 6)

References


  1. N Engl J Med. 20 May 1999; 340: 1533-8 
  2. Can J Infect Con. 2000; Spring: 9-14 
  3. Lancet. Dec 4, 1999; 354: 1932-9